Genetic relationships between obesity and osteoporosis in LGXSM recombinant inbred mice

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Genetic relationships between obesity and osteoporosis in LGXSM recombinant inbred mice.

Obesity and osteoporosis affect millions of Americans. While phenotypically, obesity is negatively correlated with fracture risk, research on a genetic basis for this relationship is lacking. We used males and females from 16 LGXSM recombinant inbred (RI) mouse strains to investigate the genetically mediated relationship between obesity and osteoporosis-related traits. First, heritabilities wer...

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Maternal genotype affects adult offspring lipid, obesity, and diabetes phenotypes in LGXSM recombinant inbred strains.

Maternal effects on offspring phenotypes occur because mothers in many species provide an environment for their developing young. Although these factors are correctly "environmental" with respect to the offspring genome, their variance may have both a genetic and an environmental basis in the maternal generation. Here, reciprocal crosses between C57BL/6J and 10 LGXSM recombinant inbred (RI) str...

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Genetic Diversity and Relationships of Agronomic Characters in Wheat Recombinant Inbred Lines

Objective: Wheat is the most important crop in Iran. Self sufficiency in wheat production is one of the economic and food safety policies in the country. In spite of the efforts which have been made in this area, the mean of wheat yield in Iran is less than its world average. Methods: In order to identifying of the high yielding wheat lines with optimal characteristics and to determine the trai...

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Genetic Diversity and Relationships of Agronomic Characters in Wheat Recombinant Inbred Lines

Objective: Wheat is the most important crop in Iran. Self sufficiency in wheat production is one of the economic and food safety policies in the country. In spite of the efforts which have been made in this area, the mean of wheat yield in Iran is less than its world average. Methods: In order to identifying of the high yielding wheat lines with optimal characteristics and to determine the trai...

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Genetic regulation of mup production in recombinant inbred mice.

Inbred strains of mice excrete all three major urinary proteins (mups) when induced by testosterone, but differ as to the relative proportions and total levels of each mup present. We have now determined the urinary mup phenotypes before and after testosterone treatment of seven recombinant inbred strains derived from progenitor strains exhibiting different mup phenotypes. The results confirm p...

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ژورنال

عنوان ژورنال: Genetics Research

سال: 2008

ISSN: 0016-6723,1469-5073

DOI: 10.1017/s0016672308009798